McGuire Gibson is one of the world's leading authorities on ancient Mesopotamia. He has done fieldwork in Iraq and elsewhere in the region and has published extensively. He was as part of a National Geographic delegation visiting Iraq to inspect archaeological sites in 2003.
He also has provided expert advice to UNESCO and other cultural and scholarly organizations working to preserve the archaeological heritage of Iraq. His fieldwork has taken him to Nippur, the religious center of ancient Mesopotamia. Additionally, he has done fieldwork in Yemen, Saudi Arabia and northeastern Syria. In 1992, he and colleague Augusta McMahon published Lost Heritage: Antiquities Stolen from Iraq's Regional Museums, the first academic publication to call attention to the problem of looting after the first Gulf War. He also is the author and co-author of numerous articles and books on ancient Mesopotamia.