Manyuan Long is interested in various issues of molecular evolution, especially on how genes with novel functions originate. Long’s group identified numerous new genes in Drosophila melanogaster (fruit fly) and mammalian genomes using experimental and computational genomic analysis. Using molecular analysis, they revealed some important molecular evolutionary mechanisms responsible for the current gene structures of the organisms they study. Furthermore, they observed a significant role of the adaptive evolution in the determination of the fate of those new genes and also interesting patterns and phenotypes associated with these new genes.
Long received his Ph.D. degree in genetics from the University of California, Davis in 1992. He joined the University as an assistant professor at the Department of Ecology and Evolution and the College in 1997, and became a full professor in 2005.