- Leon O. Jacobson Professor of Medicine
- Chairman, Committee on Clinical Pharmacology and Pharmacogenomics
- Associate Director for Clinical Sciences, Cancer Research Center
Dr. Ratain is interested in the pharmacogenetics of anticancer agents and phase I and phase II drug studies. Dr. Ratain's research is focused on the metabolism of specific anticancer agents. He has demonstrated the critical importance of genetic variants in determining variability in the pharmocogenetics and toxicity of certain anticancer drugs. His research has become a model for understanding variability in response to newer targeted drugs.